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Coronavirus cure: When will we have a drug to treat it?

More than 150,000 people have died with Covid-19, but there are still no drugs proven to help doctors treat the disease. What work is being done to find treatments? More than 150 different drugs are being researched around the world. Most are existing drugs that are being trialled against the virus. The World Health Organization (WHO) has launched the Solidarity trial aimed at assessing the most promising treatments The UK says its Recovery trial is the the world's biggest, with more than 5,000 patients already taking part And multiple research centres around the world are attempting to use survivors' blood as a treatment What types of drugs might work? There are three broad approaches being investigated: Antiviral drugs that directly affect the coronavirus's ability to thrive inside the body Drugs that can calm the immune system - patients become seriously ill when their immune system overreacts and starts causing collateral damage to the body Antibodies, either from survivors' blood or made in a lab, that can attack the virus What is the most promising coronavirus drug? Dr Bruce Aylward, from the World Health Organization, said remdesivir was the only drug that showed any signs of effectiveness, after he visited China. The antiviral drug was originally designed to treat Ebola, but other options proved more effective. It has since been shown to be effective at treating other deadly coronaviruses (Middle East respiratory syndrome and severe acute respiratory syndrome) in animal studies, leading to hopes it will also be effective against the Covid-19 coronavirus. Leaked results from trials led by the University of Chicago also suggested the drug was effective. It is one of the four drugs in the WHO Solidarity trial and its manufacturer, Gilead, is also organising trials. Can HIV drugs treat coronavirus? There has been much talk, but little evidence, that a pair of HIV drugs - lopinavir and ritonavir - would be effective at treating coronavirus. There has been some evidence they can work in the laboratory, but studies in people have been disappointing. The combination did not improve recovery, reduce deaths or lower levels of the virus in patients with serious Covid-19. However, as the trial was conducted with extremely sick patients (nearly a quarter died) it may have been too late in the infection for the drugs to work. Can malaria drugs stop coronavirus? Malaria drugs are part of both the Solidarity and Recovery trials. Chloroquine, and a related derivative, hydroxychloroquine, may have antiviral and immune-calming properties. The drugs have been thrust into the spotlight as potential coronavirus therapies, largely due to claims made by President Trump, but there is still scant evidence on their effectiveness. Hydroxychloroquine is also used as a treatment for rheumatoid arthritis, because it can help regulate the immune system. Laboratory tests have shown it can inhibit the coronavirus, and there is some anecdotal evidence from doctors saying it appears to help patients. However, the WHO says there is no definitive evidence of its effectiveness. Read More At :: กลุ่มลับไลฟ์สด18+ ดูหนังออนไลน์ HD แทงบอลสเต็ป188BET

Coronavirus: Singapore spike reveals scale of migrant worker infections

Singapore has seen its biggest number of new cases in a single day, driven by increased testing of foreign workers. Once praised for its success in containing the virus, Singapore is now facing a surge of infections linked to industrial worksites and tightly packed worker dormitories. On Thursday, 728 new cases were reported, bringing the total number of cases to 4,427. Almost 90% of these infections have been linked to these workers. The number is expected to rise as more workers get tested in the coming days to help identify the scale of the problem. Around 300,000 low-wage workers, mostly from South Asia, work in Singapore in construction and maintenance. Most of them live together in huge dormitory complexes on the outskirts of the city they've helped build. Singapore is currently in its own version of a semi-lockdown, which it refers to as a "circuit breaker". Under this, all non-essential businesses are closed, non-essential worker must stay at home and social gatherings of all sizes in both public and private spaces have been banned. Singapore's new quarantine zones Of the 728 new cases reported on Thursday, 654 were residents of dormitories. The biggest dormitory cluster, S11 Dormitory @ Punggol, now accounts for a total of 979 confirmed cases, 22% of all cases in the country. Thousands of healthy workers have now been moved out to floating dormitories, sports halls and vacant public housing buildings in an attempt to isolate them and minimise the risk of infection. Read More At :: หลุดไลฟ์สด ภาพหลุด เว็บแทงบอลออนไลน์

Coronavirus: TikTok donates £5m to Royal College of Nursing fund

Video-sharing app TikTok is giving £5m to a British nursing fund, to help it during the coronavirus outbreak. The Royal College of Nursing will use the money to provide financial support to frontline nurses facing hardship. It is the biggest donation made by a social media company to date to a British organisation involved in tackling the pandemic. The gift is part of a wider $250m (£198m) worldwide fund the Chinese firm has set up to provide relief. Not all that sum is being given away in the form of cash. A total of $125m is being offered in the form of ad credits, which are being divided up between small-to-medium sized businesses, non-governmental organisations, local authorities and health bodies. TikTok and other social media firms are currently facing increased scrutiny over their efforts to tackle misinformation about Covid-19 on their platforms. This is "an extremely sensitive public policy moment for them all," commented Carl Miller, research director of the centre for the analysis of social media (CASM) at the think tank Demos. "Platforms like Facebook and Twitter and TikTok have become our public space. "They know they are on another frontline themselves [and] governments may well legally require the tech giants to deal with misinformation." Dancing medics TikTok's action follows a pledge by Twitter's chief executive to donate $1bn of his personal stake in digital payments firm Square to fund "Covid-19 relief". Jack Dorsey described it as representing 28% of his financial worth. In April, Facebook pledged $25m to support healthcare workers on the frontline, as well as matching $2m in donations to relief efforts and a further $100m grant to small businesses. The social media company has also donated its emergency reserve of 720,000 masks to healthcare providers. TikTok intends its move to be seen as a show of solidarity with nurses, many of whom have posted videos to its platform over the past month. Videos featuring the hashtag #NHS have had over 189 million views on the app, with the top search results featuring hospital nurses and doctors dancing to popular music. "Despite the huge challenges frontline healthcare workers face on a daily basis, I have been enormously heartened by what we are seeing on our platform," said the tech firm's UK general manager. Health secretary Matt Hancock said: "I'm delighted that TikTok is supporting the RCN Foundation which brings so much support to so many." Read More At :: หลุดไลฟ์สด ภาพหลุด เว็บแทงบอลออนไลน์

NHS boss: 'I need gowns, can I call Burberry?'

The director of a large NHS trust has contacted the BBC asking for the phone numbers of Burberry and Barbour because he does not have enough gowns for his staff working on coronavirus wards. He said his trust has "less than 24 hours supply and [with the] weekend coming up" he was hugely concerned. The BBC is not disclosing his name or the trust he runs. The Department of Health said it was working "around the clock" to provide protective equipment where needed. For a number of weeks, Prime Minister Boris Johnson and government ministers have said during press briefings and interviews that Burberry will begin making personal protective equipment (PPE) on behalf of the government as one of the answers to a critical shortage. Burberry said at the end of March it would repurpose its trenchcoat factory in Castleford, West Yorkshire, to make non-surgical gowns and masks for hospital patients. The government has been criticised for not providing enough PPE for NHS and other care workers to protect them while looking after patients with the virus. Latest statistics revealed the UK recorded another 861 coronavirus-related deaths in hospital, taking the total to 13,729. The overall figure does not include hundreds more who have died in residential and nursing homes. On Thursday, as Foreign Secretary Dominic Raab announced the extension of lockdown restrictions for "at least" another three weeks, he said there remained "issues with the virus spreading in some hospitals and in care homes". Among five conditions he said must be met before curbs on daily life could be lifted were making sure the NHS could cope and ensuring PPE supplies could meet demand. Last week, Health Secretary Matt Hancock said there was "enough PPE to go around, but only if it's used in line with our guidance", adding there was a "huge task" to make sure those who need it get it. However, on Monday, Chris Hopson, from NHS Providers in England which represents hospital trusts, said it was "all really hand-to-mouth in terms of gown delivery" and called for a "more sustainable" supply. And on Wednesday the NHS Trust director told the BBC: "The official line that we don't have a shortage of PPE is fantasy." A gown is a piece of PPE used to protect the body of those who might come into contact with coronavirus. It should be made of water-resistant material and have long sleeves. If the gown is not water resistant, a waterproof apron is needed underneath to protect the wearer from droplets containing the virus. The shortage of non-surgical gowns is a critical problem facing the NHS as it struggles to secure enough kit for frontline staff. The situation at this particular trust is so critical that single use PPE is being reused. A leaked Public Health England document this week advised health workers to reuse protective gowns and masks only as a "last resort". The boss added "Trusts are already decontaminating PPE for reuse. I have several examples". Read more at :: หลุดไลฟ์สด ภาพหลุด เว็บแทงบอลออนไลน์

Wildfires 'edge closer to Chernobyl nuclear plant'

Forest fires that have been burning for several days in northern Ukraine are now no more than a few kilometres from the abandoned Chernobyl nuclear plant, reports say. Tour operator Yaroslav Emelianenko said one had reached the abandoned town of Pripyat, which used to serve the plant. He said it was now just 2km (1.24 miles) from where the most dangerous waste from the plant was stored. Greenpeace said the fires were much bigger than the authorities realised. The NGO's Russia branch, quoted by Reuters, said the largest fire covered 34,000 hectares, while a second fire just a kilometre from the former plant was 12,000 hectares in area. Mr Emelianenko also said that if the fire engulfed Pripyat it would be an economic disaster, as supervised tourist visits provided valuable revenue. In 2018 more than 70,000 people visited the town. Last year that figure was even higher, after the success of an HBO mini-series about the disaster. Firebreaks around the plant Police said the fire had been burning since the weekend of 4 April, after a man set fire to dry grass near the exclusion zone. It has since moved closer to the nuclear plant. More than 300 firefighters with dozens of pieces of special hardware are reportedly working at the site, while six helicopters and planes are attempting to extinguish the fire from above. Kateryna Pavlova, acting head of the State Agency of Ukraine on Exclusion Zone Management, told the Associated Press news agency that they “cannot say the fire is contained”. “We have been working all night, digging firebreaks around the plant to protect it from fire,” she said. On 5 April Yegor Firsov, acting head of Ukraine’s state ecological inspection service, said in a Facebook post that radiation levels in the area had risen substantially above normal. Government officials later rejected this finding, and said the levels in the area were “within normal limits”. Mr Firsov also withdrew his remarks. Read more at :: เว็บแทงบอลที่ดีที่สุด หลุดกลุ่มลับ หลุดไลฟ์สดพริตตี้

Coronavirus: Don't expect changes to UK lockdown this week - Dominic Raab

The government does not expect to make changes to coronavirus lockdown restrictions this week, Dominic Raab has said. The foreign secretary said the UK's plan "is working" but that "we are still not past the peak of this virus". "Keep this up, we have come too far, lost too many loved ones and sacrificed too much to ease up," he said. It came as the government said it might change its advice to the public on wearing face masks outdoors. Will face masks become the new norm? The UK's chief scientific adviser Sir Patrick Vallance told the daily Downing Street news conference the guidance was subject to an ongoing review. He added that the government had already seen "more persuasive" data suggesting masks can stop a person passing the virus to someone else, rather than preventing them from catching it. The World Health Organization said it remains the case that medical masks should be reserved for healthcare workers, not the general public. Meanwhile, Sir Patrick warned the number of deaths recorded in the UK is likely to rise in the coming days before they could plateau. He said: "I think this week we are going to see a further increase, thereafter we should see a plateau as the effects of social-distancing come through. That plateau may last for some time and begin to decrease." Prof Chris Whitty, the UK government's chief medical adviser, told the briefing that 92 care homes had detected an outbreak of coronavirus in the last day alone. "If an outbreak is suspected public health authorities will go in to do testing to check if an outbreak has taken place," he said. The Department of Health later confirmed to the BBC that coronavirus outbreaks have been detected at 2,099 facilities in England so far. Prof Whitty added that he would like to have "much more extensive testing" in care homes due to the "large numbers of vulnerable people" there. "One of the things we want to do is to extend the amount of testing of people in care homes as the ability to test ramps up over the next few weeks," he said. Liz Kendall, Labour's shadow minister for social care, called on the government to publish daily figures of deaths in care homes "so we know the true scale of the problem and how fast it is spreading". It came as 13 residents of one 72-bed care home in County Durham were confirmed to have died after displaying symptoms of coronavirus. Read more at :: หลุดกลุ่มลับ หลุดไลฟ์สดพริตตี้ เว็บแทงบอลที่ดีที่สุด

Premier League injuries: Who could yet play again in delayed season?

Jose gets his main man back Perhaps the biggest gain from a delayed Premier League season, Tottenham striker Harry Kane says he is likely to be back to full fitness once football resumes. The England captain is ahead of schedule in his recovery from surgery on a hamstring injury he suffered on 1 January. Jose Mourinho ruled forward Son Heung-Min out of the rest of Spurs' season back in February when the South Korean broke his arm but he could now also play again - if he comes back from national service in good nick. All South Korean men must complete military service by the age of 28. Son, who turns 28 in July, was given permission to return to his homeland last month to continue his recovery from a fractured arm. Tottenham say the forward will return to London after the completion of his military service in May. Fellow attacker Steven Bergwijn is another who was ruled out for the season with an ankle injury but could now be back on the pitch. Tottenham's season was looking in danger of collapsing before the suspension but, if football does resume with the return of their key man, a top-five finish could still be a realistic aim. The Premier League suspension could yet see some players playing more of a part in the rest of the campaign than they expected It's now been over a month since we had any Premier League action, and we are still no clearer on when the beautiful game will return. There are a few players for whom the indefinite delay might help them play more of a part in the season than they thought. Which clubs are likely to be affected on the field and could it impact on any potential issues in the table? We took a closer look. Read more at :: หลุดกลุ่มลับ หลุดไลฟ์สดพริตตี้ เว็บแทงบอลที่ดีที่สุด

Fears over rapid spread in Italy's south

The Italian region hardest hit by coronavirus has seen a steep decline in the number of deaths and infections but worries are growing that the country's south could become the next hotspot. Recent numbers from the northern region of Lombardy suggested the epidemic might be slowing at its epicentre. But poorer southern parts are seeing a sharp rise in deaths, raising fears the health service could be overwhelmed. Italy has reported 8,215 deaths from coronavirus and 80,539 confirmed cases. A four-day trend of a slight decline in the number of cases ended on Thursday when both infections and deaths rose compared to the previous 24-hour reporting period. Italy is the worst-affected in Europe where almost everything has been closed for over two weeks and people told to stay at home. What is happening in Italy's south? Contagion and deaths are far less widespread there, but worrying signs are coming from regions such as Campania around Naples and Rome's Lazio where the health system is considered much less equipped than in the rich north. So far there have been 74 deaths in Campania and 95 in Lazio. In an open letter to Prime Minister Giuseppe Conte, Vincenzo De Luca, president of the Campania region, complained that the central government had not provided promised ventilators and other life-saving equipment. "At this point there is the real prospect that Lombardy's tragedy is about to become the south's tragedy," he said. "We are on the eve of a major expansion of infections which may not be sustainable." On Thursday, Mr Conte told the Italian Senate that all of Europe would be hit by a "hard, severe" recession following the coronavirus emergency, and that "extraordinary and exceptional measures" were needed to face the shock. With analysts predicting that the strict measures will result in Italy sliding into its deepest recession in a generation, Mr Conte promised a second stimulus package worth at least €25bn (£23bn; $27bn). Read more at :: กลุ่มลับไลฟ์สด สมัครเข้ากลุ่มลับ เว็บแทงบอล

Supermarkets to get government list of vulnerable people

upermarkets will use a government database of 1.5 million vulnerable shoppers to help prioritise delivery slots during the coronavirus pandemic. Sainsbury’s and Waitrose say they will begin writing to people on the list next week. There is concern those most in danger from the virus are going in to stores due to a lack of online shopping slots. People in high-risk households have told the BBC they are struggling to get priority treatment online or in stores. 'I'm terrified of going to the shops' Sharon Cranfield from Tadworth in Surrey says her 19-year-old daughter Jessica is very vulnerable to coronavirus because she has cystic fibrosis, which means she needs an "athlete-style" diet of 3,000 to 4,000 calories a day to survive. The government says people should book home deliveries where possible, especially if they share a household with someone who is especially vulnerable to catching the virus. But Sharon has struggled to book an online slot. "It's so risky and I can't put that risk on my daughter. I just hope they get those delivery slots sorted. "There's a misconception about the vulnerable being old. A lot of people with cystic fibrosis are children and they can't look after themselves. It's just so stressful. My anxiety levels have gone through the roof." 'I'm forced to mix with people' Norman Philips, aged 68, cares for his wife and his 91-year-old mother, who both have dementia, but he is not old enough to be allowed to shop early. Many supermarkets have started to set aside the first hour of trading on certain days for the over-70s, but this does not extend to those caring for them. But Mr Philips told the Today programme he was unable to secure a slot for online delivery of his groceries, because the first slot available was two weeks away. Facing a huge surge in demand, online shopping sites have been crashing, temporarily closing, or considerably oversubscribed. As a result, he had to brave huge queues at his local Sainsbury’s. “I’m forced to go mixing with people and then come back to a home which has got someone who is supposed to be being shielded and another, my mum, who is in the high-risk category,” he said. He said he had been told by social services to call the supermarket and get his name on a priority list, but despite waiting on the phone for two-and-a-half hours, he was unable to get through. Supermarkets limit shoppers as rules tighten Morrisons taking on charity shop staff Another shopper, Claire from Orpington, contacted Radio 5 live’s Wake Up To Money programme to say that although she is disabled, her needs are being overlooked. “I personally am blind and have a serious heart condition which, while it doesn't put me on the list in terms of being immune-suppressed etc, does carry a risk of serious complications should I catch the virus,” she said in a text message. “But apparently, I and others like me don't count as any kind of priority and as such, we either take our chances that a slot may become available, or risk catching the virus with the added complications if we go out.” Claire added it was difficult for blind people to observe the social distancing guidance of staying two metres away from other people, since they had to be guided round a shop. Read more at :: กลุ่มลับไลฟ์สด สมัครเข้ากลุ่มลับ เว็บแทงบอล

US overtakes China with most cases

The US now has more confirmed cases of coronavirus than any other country, with more than 85,500 positive tests. According to the latest figures collated by Johns Hopkins University, the US has overtaken China (81,782 cases) and Italy (80,589). But with almost 1,300 Covid-19-related fatalities, the US death toll lags behind China (3,291) and Italy (8,215). The grim milestone came as President Donald Trump predicted the nation would get back to work "pretty quickly". How did the White House react? Asked about the latest figures at a White House briefing on Thursday afternoon, President Trump said it was "a tribute to the amount of testing that we're doing". Vice-President Mike Pence said coronavirus tests were now available in all 50 states and more than 552,000 tests had been conducted nationwide. Trump says US tested more than S Korea - is he right? Mr Trump also cast doubt on the figures coming out of Beijing, telling reporters: "You don't know what the numbers are in China." Does the president still hope to ease restrictions? Mr Trump has set a much-criticised goal of Easter Sunday, 12 April, for reopening the country. That plan seemed to gather impetus on Thursday as it emerged an unprecedented 3.3 million Americans have been laid off because of the virus. At Thursday's briefing, he said: "They [the American people] have to go back to work, our country has to go back, our country is based on that and I think it's going to happen pretty quickly. "We may take sections of our country, we may take large sections of our country that aren't so seriously affected and we may do it that way." He added: "A lot of people misinterpret when I say go back - they're going to be practising as much as you can social distancing, and washing your hands and not shaking hands and all of the things we talked about." He promised more details next week. What could he be planning? In a letter to state governors on Thursday, Mr Trump said his team plans to release federal social distancing guidelines that may advise some regions to loosen restrictions. Mr Trump wrote of a "long battle ahead" and said "robust" testing protocols might allow some counties to lift their safeguards against the coronavirus. He said the "new guidelines" would create low, medium and high risk zones that would allow the government to advise on "maintaining, increasing, or relaxing social distancing and other mitigation measures they have put in place". On Thursday night, Mr Trump phoned in to Fox News host Sean Hannity's programme and said he believed Iowa, Idaho, Nebraska and parts of Texas could reopen earlier than other states. The plan emerged as new research on Thursday estimated Covid-19-related deaths in the US could top 80,000 over the coming four months - even if people observe strict social distancing. As many as 2,300 patients could be dying every day by April, according to the study from the Institute for Health Metrics and Evaluation at the University of Washington's School of Medicine. Read more at :: กลุ่มลับไลฟ์สด สมัครเข้ากลุ่มลับ เว็บแทงบอล